Do you feel depressed? Are you on The Pill? There might be a correlation.
A new study published in the Journal of the American Medical Association (JAMA) followed 1M+ women ages 15-34, with average age of 24. The longitudinal study followed Danish women from 1995 to 2013 who had no prior history of depression. The average time between follow-ups was 6+ years.
Women who were on a combination of oral contraceptives were “23% more likely to be prescribed an antidepressant,” usually within the first six months after beginning the Pill’s regimen. But women on the progestin-only pills (a synthetic form of the progesterone hormone) were “34% more likely to take antidepressants or get a first diagnosis of depression” than women who didn’t take the hormonal contraceptive.
The risk primarily targets teenagers, and the risk inversely correlates with age (i.e. the risk decreases as one gets older).
It’s suggested that higher levels of progesterone may lower mood (which is controlled by estrogen). But researchers noted that women are twice as likely to be diagnosed with depression than men within their lifetime, so the study’s findings are something to consider. It should be noted that the researchers have called for more follow-up studies to corroborate these findings.