Felicity Huffman as Bree in ‘Transamerica’ (Women Onscreen)

In 2005’s “Transamerica,” Felicity Huffman plays Bree, a transgender woman who learns she has a son Toby (Kevin Zegers). She bails Toby out of jail, and they take a cross-country road trip where Toby learns of Bree’s true relation to him.

Huffman won the Best Actress in a Drama Golden Globe Award, and received a nomination for the Best Actress Oscar.